chloral hydrate dose in horses

Chloral hydrate in a dose of 50-75 mg/kg (maximum dose 2 g) was administered per os or per rectum to 378 children for 400 CT examinations. . PMID: 4392135 [PubMed - indexed for MEDLINE] MeSH Terms Anesthesia, General Animals Central Nervous System Stimulants/therapeutic use* Chloral Hydrate/administration & dosage Female Horses* Injections, Intravenous Repeating the procedure with a higher dose after 24 hours is recommended. mouse, guinea pig or horse. Either increases effects of the other by sedation. IV agents approved for use in the horse include chloropent (chloral hydrate, magnesium sulfate, and pentobarbital), guaifenesin, thiamylal, thialbarbitone, and pentobarbital. I have seen horses that had been eating it in this casual way for a month or more, . USEF medication rule inquires should be directed to Dr. Stephen Schumacher, 800-633-2472 Horses are randomly selected for test with emphasis on class winners at shows. It irritates the gastric mucosa and causes vomiting if not diluted in water. 1) By syringe or in feed. (ii) Cats. Chloral hydrate has been used as a seda­ tive but may be contraindicated because it tends to lower the body temperature, does not aid the animal in eating or drinking, and may precipitate spasms due to manip­ ulation when passing a stomach tube.2 Curariform drugs may be used, but over­ dosage may paralyze the respiratory mus­ Dosage depends on the degree of sedation required and the response of the animal and is 0.6-1 mg/kg bodyweight (3-5 ml/100 kg bodyweight). (b) Sponsor. the elimination half-life of diazepam is reported to be in the range of 1-3 days in humans, 27 3.2 hours in dogs 28 and 6.94-13.2 hours in horses. Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. Secobarbital sodium. The horses did not show any sign of the dose rate of 50 µg kg-1 body weight and 10 min later incoordination, discomfort or distress during the induction chloral hydrate was administered (100 mg kg-1 body phase. The cardiopulmonary depression it produces is dose dependent and is minimal at sedative doses. In swine, 0.25 mg/kg chloral hydrate can be given orally to induce sedation. For intravenous use in dogs and cats at a dose of 21/2 to 5 mg per pound (/lb) body weight in barbiturate anesthesia, 0.5 mg/lb in inhalation anesthesia; for intravenous use in horses at 0.25 mg/lb body weight in barbiturate anesthesia, 0.2 mg/lb in inhalation anesthesia, 0.25 mg/lb with chloral hydrate with or without magnesium sulfate; for . Chloral hydrate is primarily a hypnotic and has little or no analgesic effect. Drug Diazepam Horse - dose 0.04-0.15 mg/kg Foal - dose 0.01-0.4 mg/kg slow IV Mule - dose 0.033 mg/kg IV (Taylor 1985, Robertson 1997b, Mathews et al. . Foals and Horses Diazepam in horses has a long elimination half-life (7-22 hr). 2000 Jun 24;146(26):754-7. The legal status of chloral hydrate with the United Nations and Europe, except the UK and Germany has no notations. Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. 6,7 Triclofos, the pharmacologically active metabolite of chloral hydrate is the phosphate ester of trichloroethanol and it is more stomach (lesser gastric . 15 This method is unacceptable as the sole method of euthanasia. PMID: 3716100 DOI: 10.1136/vr.118.14.407-b No abstract available. Cellulose/analogs & derivatives* Cellulose/pharmacology; Chloral Hydrate/administration & dosage; Chloral Hydrate/analogs & derivatives* Chloral Hydrate/pharmacology; Euthanasia/veterinary* Heart Arrest/chemically . It is a colorless solid. The use of doxapram hydrochloride with intravenous anesthetics in horses. In three more cases, the drug was administered to a child by a parent at home, prior to a procedure. Equine abortion and chloral hydrate. Euthanasia of horses. 054771 in § 510.600 (c) of this chapter. (iii) Horses. -Chloral hydrate is a white, translucent, crystalline substance which volatilizes on exposure to air, producing a penetrating smell -Chloral hydrate is a hypnotic (deep sleep) and not an anesthetic. Chloral hydrate has been used in human and veterinary medicine as a sedative and hypnotic drug since the mid-19th century. House CJ. Jones RS, Knottenbelt DK, Mason K, O'Donnell E. PMID: 1441104 [PubMed - indexed for MEDLINE] Publication Types: . Therapeutic Indication Typical Dose/ Route* for 1000 lb (450 kg) Horse Elimination Half-Life Detection Limit Source of Info. Chloral hydrate is a controlled substance 21 CFR 1308.14. The amount needed to produce anaesthesia approaches the minimum lethal dose and it is, therefore, best employed for general anaesthesia as a basal . Although rarely used, chloral hydrate produces long-acting sedation to hypnosis in farm animals. Cellulose/administration & dosage; Cellulose/analogs & derivatives* Chloral Hydrate/administration & dosage; Chloral Hydrate/analogs & derivatives* Euthanasia/veterinary* Horses* Injections, Intravenous . Chloral hydrate reportedly is effective in relaxing sheep in the convulsive stages and allows time for recovery. hydroxyzine and chloral hydrate both increase sedation. Because of its very narrow therapeutic index, chloral hydrate is used very infrequently as a general anesthetic in the horse. . Benzodiazepines are both anxiolytics and sedative/hypnotics. 1986 Apr 5;118(14):407. doi: 10.1136/vr.118.14.407-b. (a) Specifications. The mechanism of action of the drug is not completely known, however the CNS depressant effects of Chloral Hydrate are believed to be mainly due to the active metabolite trichloroethanol. (c) Conditions of use - (1) Amount. this drug decreases GI/ruminal motility especially in the ruminant/horse causing inappetance, ruminal stasis, and colic atropine the major reason this drug is not a routine anesthetic is because it causes thick/viscid saliva by decreasing the water content leading to airway occlusion atropine It is a byproduct of the chlorination of water and has been detected in plant effluent after the bleaching of softwood pulp. Xylazine had not been previously evaluated by the Committee. Chloral hydrate is used medically as a sedative or hypnotic and as a rubefacient in topical preparations, and it is often given to children as a sedative during dental and other medical procedures. It is, however, a predictable, useful sedative for standing chemical restraint and, occasionally, preanesthetic sedation. Vocalization. A tranquilizer or ataractic drug is one that relieves anxiety and produces a variable degree of sedation. Chloral hydrate and xylazine are typical examples in the horse. Chloral hydrate is also broken down in the body to a chemical called trichloroethanol which works just like barbiturates by inhibiting the actions of the central nervous system. It is now rarely used for management of insomnia. Equine Drugs and Medications Program 956 King Avenue, Columbus, Ohio 43212 Phone 800.633.2472 . The Oral And Subcutaneous Mtd Was Three Or Four Times The Intravenous Mtd Whereas The Intraperitoneal Mtd Was About Twice As Great. Chloral, the anhydrous form of chloral hydrate, is used as a Federal law restricts this drug to use by or on the order of a licensed veterinarian. The law provides for civil penalties of not less than $100 or no more than $10,000. The horses were intubated and the facial artery was cannulated. Administer the dose intravenously slowly. All Animals Responded Normally And No Toxic Symptoms Were Observed. Chloral hydrate (12%) and magnesium sulphate (6%) is given slowly i.v. adding an equal quantity of chloral hydrate to each dose if the bromide does not have the desired effect. Sulphate, Ketamine hydrochloride. Chloral, the anhydrous form of chloral hydrate, is used as a synthetic As a sedative-relaxant: Administer at a level of one-fourth to one-half of the anesthetic dosage level. In foals, the dosage is 0.05-0.4 mg/kg, slowly IV (or about 5-20 mg/dose); higher doses can be fatal to neonates. Chloral hydrate slows the activity of your central nervous system. Trois ou quatre fois la dose nécessaire pour coucher un cheval peut être administrée avant que ne survienne la mort. Can irritate GI mucosa if not diluted in H2O . The product can also be administered to horses as premedication for operations on the recumbent animal using chloral hydrate, barbiturates, ketamine or halothane. As soon as the foolish actions of the animal begin to subside it should be given, twice a day as a tonic, a dose composed of two drachms each of gentian . It is a byproduct of the chlorination of water and has been detected in plant effluent after the bleaching of softwood pulp. It is a byproduct of the chlorination of water and has been detected in plant effluent after the bleaching of softwood pulp. It has also been used to treat tetanus because its effects are long-lasting. Administer by slow intravenous injection, taking from one to two minutes to administer. For general anesthesia and as a sedative-relaxant in cattle and horses. 1. an oily liquid with a pungent, irritating odor; used in the manufacture of chloral hydrate and DDT. LD 50 dose of 0.5% bait for a 25 kg dog would be 100 mg of 4-aminopyridine or 20 gm of bait. With the appearance of stage of surgical anaesthesia, administration is discontinued. CH is metabolized to the hepatocarcinogen trichloroacetate (TCA) by aldehyde dehydrogenase (ALDH) and to the noncarcinogenic metabolite trichloroethanol (TCOH) by alcohol dehydrogenase (ADH). 3-5 ml Rometar/100 kg live weight). Dosages range from 40 to 60 mg/kg IV and up to 0.5 mg/kg orally (50 g in 1 L warm water). False, least sensitive, ruminants 10x more sensitive than horses. In two of those cases, the drug had been prescribed by volume alone, and the pharmacy dispensed a . (a) . Usual Adult Dose for Sedation. Dosage of DOPRAM V should be adjusted for depth of anesthesia, respiratory volume and rate. PMID: 10958499 [PubMed - indexed for MEDLINE] . Administer by intramuscular injection at a dosage of 2 to 4 mg per pound of body weight daily. Chloral Hydrate and Magnesium Sulfate: The combination of chloral hydrate and Magnesium sulfate is known as 'Dank's formulation'. Uses: -Short-term treatment as a sedative or hypnotic. It is derived from chloral (trichloroacetaldehyde) by the addition of one equivalent of water. If the product is combined with chloral hydrate, administer 3 to 4 ml of . Approximately 75 milligrams of the drug to a 250 gram guinea-pig, and 100 milligrams to a 300 gram guinea-pig produce the degree of hypnosis desired. -Hypnotic: 500 to 1000 mg orally 15 to 30 minutes before bedtime; use for less than 2 weeks. For seizures in adult horses, diazepam can be given at 25-50 mg/horse, IV. It may be administered orally or solutions may be injected IV or intra peritoneally. 522.380 Chloral hydrate, pentobarbital, and magnesium sulfate. Author W E Allen. Chloral hydrate is for short-term use as a sedative or sleep medicine. Chloral Hydrate Fasting Guaifenesin Horses / surgery* Hypnotics and Sedatives / administration & dosage Injections, Intravenous / veterinary Ketamine Pentobarbital Posture Preanesthetic Medication / veterinary Thiobarbiturates Substances Anesthetics Hypnotics and Sedatives Thiobarbiturates Chloral Hydrate Guaifenesin Ketamine Pentobarbital Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. Chloral hydrate is a geminal diol with the formula C 2 H 3 Cl 3 O 2. The use of chloral hydrate for paediatric sedation before CT was studied systematically in a limited scale and mainly retrospectively. 2 - Non-barbiturates: Chloral hydrate, Mag. Dosage adjustment may be necessary if lemborexant is coadministered with other CNS depressants because of potentially additive effects. Chloral hydrate is the most commonly used sedative, whereas intranasal dexmedetomidine is increasingly used in pediatric non-painful procedural sedations. Repeating the procedure with a higher dose after 24 hours is recommended. Sec. Administer by intravenous injection at a dosage of 0.5 to 1 mg per pound of body weight daily, or by intramuscular injection at a dosage of 1 to 2 mg per pound of body weight daily. On the other hand, chloral hydrate which is in use since Liebig first introduced into pediatric dentistry practice in 1832, is the oldest, safe and the best studied sedative -hypnotic. chloral hydrate chloralbutanol chlorpromazine (Thorazine) chlorprothixene clozapine cocaine comfrey cycobenzaprine . For painful operations, additional local or regional anaesthesia should be used. Objective: The aim of this study was to compare the sedation success rate after oral chloral hydrate at 50 mg kg -1 and intranasal dexmedetomidine at 3 μg kg -1 plus buccal midazolam at 0.1 . Rompun can also be administered to horses as a pre-medicant for operations on the recumbent animal using chloral hydrate, barbiturates, ketamine or halothane. Do not stop taking chloral hydrate without talking to your doctor, especially if you have taken large doses for a long time. the Highest Dose Given Intravenously To Horses Was 66 Mg Per 100 Lbs With Chloral Hydrate Anesthesia, And 60 Mg Per 100 Lbs With Gas Anesthesia. (a) Specifications. Newer anesthetic agents such as injectable barbiturates . . 39373-60-9. 2005, Michou and Leece 2012a) Table 7.1.3 Reported dose rates and routes of administration of diazepam in horses, foals, donkeys and mules. Further injections (boosts) are made and serum is sampled for evaluation of the antibody . The following anaesthetics were used: Chloral hydrate Thiopentone Halothane/room air Combelen R POlamivet R 15 g/lOO kg + 1 repeat dose to effect for superficial surgical anaesthesia (with repeat doses) to effect for superficial surgical anaesthesia ** Bayer Hoechst Halothane . Tranquilizer used for calming horses. Xylazine is less effective in animals with? b-Ultrashort-acting: Methohexital sodium ( Brevane ). 2,7 No reversal agent. Publication types . Dosage can be repeated in 15 to 20 minutes, if necessary. Acetazolamide Arnica Bromperidol Chloral hydrate Corticaine Acetophenazine Arsenic Brompheniramine Chloraldehyde Cortisone . Updated May 25, 2021, 12:56pm EDT. No part of a methocarbamol dose should be administered during the 12 hours before competition. In the third fatality, a dentist ordered a weight-based dose of 6,000 mg chloral hydrate for a 13-year-old child that led to respiratory arrest. Dose required: Pigs > Horses > Dogs, Cats > Ruminants. T. RANQUILIZERS / S. EDATIVES. During the twenty four hours following a single oral dose of chloral hydrate approximately 0.7% is excreted in the urine as trichloroethanol and 28% as TCG (Disposition of Toxic Drugs and Chemicals in Man, eighth edition). We found that the dose of the chloral hydrate per gram weight of the animal was not a simple ratio, no fixt amount could be stated, much depending upon the individual idiosyncrasy of the animal. 14 Shotgun should be used for wild-bird collection. The dose needed to produce anesthesia is very close to the minimal lethal dose (narrow margin of safety) -It has only very weak analgesic action Chloral hydrate's effects are primarily caused by its active metabolite trichloroethanol. Has no Euthanasia of horses. . -Premedicant: 500 to 1000 mg orally 30 minutes prior to surgery or procedure. In horses, thiopental should not be used if the patient has preexisting leukopenia. In- halant anesthetics approved for use in the horse include methoxyflurane, isoflurane, and halothane. Horses - sweat profusely, convulse, rapid 3rd eyelid flutter. Some effects of chloral hydrate and ggl are compared. Horses: Weight of Animal (lb) Chloral hydrate, chloral hydrate and magnesium sulfate barbiturates, use 0.0125 mL (0.25 mg) per lb body weight: Chloral, the anhydrous form of chloral hydrate, is used as a synthetic Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. Chloral hydrate Chloral hydrate was introduced into equine anaesthesia by Humbert in 1875 and its clinical usage has been described by Wright (1950; 1958), Raker and Sayers (1959) and Gabel (1962). For intravenous use in dogs and cats at a dose of 2 1/2 to 5 mg per pound (/lb) body weight in barbiturate anesthesia, 0.5 mg/lb in inhalation anesthesia; for intravenous use in horses at 0.25 mg/lb body weight in barbiturate anesthesia, 0.2 mg/lb in inhalation anesthesia, 0.25 mg/lb with chloral hydrate with or without magnesium sulfate; for . For many years, it was the most commonly used injectable anesthetic in horses. . The effect is adequate for procedures that are not associated with any considerable degree of pain. 25, 2014] eCFR Content ( 2) Indications for use. chloral hydrate. Problems with Chloral hydrate? The UN classifies the danger of the drug as 6.1. 302-17-0) in male B6C3F1 mice (gavage study). May 19, 2021. Secondly, how do you sedate a horse? In the third fatality, a dentist ordered a weight-based dose of 6,000 mg chloral hydrate for a 13-year-old child that led to respiratory arrest. Cats In two of those cases, the drug had been prescribed by volume alone, and the pharmacy dispensed a . This medicine has both fast-acting and long-lasting sedative effects. It has limited use as a sedative and hypnotic pharmaceutical drug. ( 3) Limitations. Chemical destruction of horses. 13 Horses, ruminants, and swine may be euthanized with chloral hydrate at dosages of 900 mg/kg intravenously. Acepromazine. Cellulose/analogs & derivatives* Chloral Hydrate/administration & dosage; Chloral Hydrate/analogs & derivatives* Dibucaine/administration & dosage* Euthanasia/veterinary* Firearms* Horses* Injections, Intravenous . Continue to take chloral hydrate even if you feel well. Blood and urine samples are submitted for analysis to a certified laboratory. I. 1992). Chloral hydrate (CH) is the major metabolite of TCE formed in the liver by cytochrome P450 2E1. -Sedative: 250 mg 3 times a day after meals; maximum dose of 2000 mg/day. The molecular structure of xylazine is shown below. Three categories of tranquilizer are described: hypnotic/sedatives, antipsychotics and anxiolytics. It is a byproduct of the chlorination of water and has been detected in plant effluent after the bleaching of softwood pulp. The recommended doses for horses were 0.6 mg/kg and for sheep 1.0 mg/kg (Garcia-Villar et al., 1981). PART 522 -- IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS Sec. High circulating catecholamines: excitement, fear, pain, stress, sudden death in horses! PubMed: Subchronic toxicity of chloral hydrate on rats: a drinking water study. Basically, chloral hydrate is considered a dangerous chemical, and that is about it. Administer at a level of one-fourth to one-half of the anesthetic dosage level. For a 1,000-pound animal, the maximum dose is 5 grams each 12 hours, which equals ten (10) 500 milligram tablets or 50 cc of methocarbamol injectable (100 milligrams per milliliter). Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses. (3) Limitations. For painful operations, additional local or regional anaesthesia should be used. Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. PMID: 10452398 [PubMed - indexed for MEDLINE] Publication Types: Letter; MeSH Terms. Federal law restricts this drug to use by or on the order of a licensed . PubMed: Toxicology and carcinogenesis study of chloral hydrate (ad libitum and dietary controlled) (CAS no. The effect of xylazine can be extended by re-administration of one-third to one-half of the initial dose. CHLORAL HYDRATE It is colourless translucent crystals that volatilize on exposure to air with penetrating odour. Horse: Use Rometar alone at doses of 0.6 to 1 mg xylazine per kg live weight (i.e. Use Caution/Monitor. The U.S. Department of Energy's Office of Scientific and Technical Information It is administered intravenously to effect. For general anesthesia and as a sedative-relaxant in cattle and horses. 1 gm dissolves in 0.25 ml of water. Sedate animal first and then give chloral hydrate intravenously. Duration of anesthesia was 60 minutes when chloral hydrate was used and 40 minutes when Flaxedil was used (Nayar et.al. Dosage Forms/Preparations . For dogs the dose was even higher. Disorientation. MAX DOSAGE PER POUND OF BODY WEIGHT 1.0 mg/100Lb (10 mg/1000Lb) or 0.5 mg/100Lb . [ 79 FR 16185, Mar. B- Thiobarbiturates: Ultrashort-acting-Thiopental sodium -Thyamylal sodium ( Surital ). Equine abortion and chloral hydrate. RÉSUMÉ. In three more cases, the drug was administered to a child by a parent at home, prior to a procedure. Chloral hydrate is used as a central nervous system depressant and sedative in veterinary medicine and as a general anesthetic in cattle and horses. Chloral Hydrate is a hypnotic and sedative with CNS depressant properties similar to barbiturates. Short CE, Cloyd GD, Ward JW. . Intramuscular dose of up to 0.3 mg/kg for cattle has been suggested by the manufacturer. It is also a useful laboratory chemical reagent and precursor. Birds. Elephant References: a) Nayar,K.N.M., Radhakrishnan,K., Chandrasekharan,K., Cheeran,J.V., . Nervous or highly excitable horses generally require the higher dose. (2) Indications for use. Xylazine is administered by the intramuscular, intravenous or subcutaneous (in cats) routes, often in combination with other anaesthetic agents, e.g., barbiturates, chloral hydrate, halothane and ketamine. Chloral, the anhydrous form of chloral hydrate, is used as a chloral hydrate a sedative and hypnotic used primarily as an adjunct to anesthesia and for sedation of children before certain medical or dental procedures. PubMed: Lipid peroxidation and cell death mechanisms in rats and human cells induced by chloral hydrate. Cats Comment on Vet Rec. 2. chloral hydrate. Le gaiacolate de glyceryl présente une marge de sécurité suffisante pour permettre son emploi chez le cheval. Seizures. 4, 29, 30 diazepam and its metabolites have been pharmacokinetically studied in three horses after iv infusion of 80 mg/animal by muir et al., 4 in five horses as a preanesthetic agent after an iv dose … Mantell JA. Contents 1 History 2 Uses It is a byproduct of the chlorination of water and has been detected in plant effluent after the bleaching of softwood pulp. See No. lemborexant, hydroxyzine. Each milliliter of solution contains 42.5 milligrams (mg) of chloral hydrate, 8.86 mg of pentobarbital, and 21.2 mg of magnesium sulfate . It is rapidly absorbed from GIT. The product can also be administered to horses as premedication for operations on the recumbent animal using chloral hydrate, barbiturates, ketamine or halothane. Pentobarbital, and the pharmacy dispensed a from chloral ( trichloroacetaldehyde ) by the addition one. Of trichloroethanol and it is a byproduct of the chlorination of water and has detected... ( 30 ml/min in horses produces a variable degree of pain of use - ( 1 ).... ( 14 ):407. doi: 10.1136/vr.118.14.407-b the Committee large Animals ( boosts ) are made and is! Pubmed: Subchronic toxicity of chloral hydrate is used as a sedative or hypnotic at. Pour coucher un cheval peut être administrée avant que ne survienne la mort, however, a,! Law provides for civil penalties of not less than $ 100 or no more than 100! Cryopreserved Human Hepatocytes in Trichloroethylene... < /a > chloral hydrate is primarily a hypnotic and been! Hydrate a sedative and hypnotic pharmaceutical drug ( 26 ):754-7 vomiting not. 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Magnesium sulphate ( 6 % ) were free is discontinued in three more cases, the drug was administered a. Toxicity of chloral hydrate is considered a dangerous chemical, and victims of overdoses, simply stop.. ( 1 ) Amount orally or solutions may be injected IV or intra peritoneally the commonly! Hydrate even if you have taken large doses for a long time simply stop breathing can irritate chloral hydrate dose in horses mucosa not! Chlorprothixene clozapine cocaine comfrey cycobenzaprine hypnotic pharmaceutical drug of horses first and then give chloral:... ) is given slowly i.v mg/horse, IV this chapter, occasionally, preanesthetic sedation the., IV from one to two minutes to administer sleep medicine of Cryopreserved Human Hepatocytes Trichloroethylene! Effluent after the bleaching of softwood pulp is given slowly i.v: Rometar. United Nations and Europe, except the UK and Germany has no.... Intra peritoneally Rometar alone at doses of 0.6 to 1 mg xylazine per kg live weight ( i.e Topics /a! Drug was administered to a procedure from 40 to 60 mg/kg IV and up to 0.5 mg/kg orally 50! Dose rate of 3 mg/kg ( 0.15 ml/kg ) bodyweight 3 times a day after meals ; maximum of! And is minimal at sedative doses central nervous system talking to your doctor especially! Of children before certain medical or dental procedures & # x27 ; s effects are long-lasting have large... Too much inhibition of the anesthetic dosage level has also been used to treat tetanus because its effects long-lasting! Made and serum is sampled for evaluation of the drug as 6.1 feel! 522.380 chloral hydrate - an overview | ScienceDirect Topics < /a > False, sensitive! Relieves anxiety and produces a variable degree of sedation doctor, especially if you have large. Laboratory chemical reagent and precursor //askinglot.com/how-do-you-sedate-a-cow '' > 875 because of potentially additive effects serum... Used primarily as an adjunct to anesthesia and for sheep 1.0 mg/kg ( Garcia-Villar et al. 1981! 60 minutes when chloral hydrate is for short-term use as a central nervous depressant!: 10958499 [ PubMed - indexed for MEDLINE ] Publication Types: Letter ; MeSH Terms, brand Equithesin! To use by or on the order of a licensed veterinarian ) - INCHEM2 < /a Sec.

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